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Organ protection studies in animal models of chemotherapy-induced damage and traumatic brain injury show BPC-157's cytoprotective reach across multiple tissue types

In vitro functional analyses confirmed their mature hepatocyte characteristics: they showed high transcription and protein expression of ALB, A1AT, CYP3A4, and CYP2C9, comparable to primary human hepatocytes (PHs)

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Niedernhofer, J.F

The liberated p53 then transcription-independently activates the pro-apoptotic protein BAX, thereby triggering the execution phase of apoptosis