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Methods Animals and experimental design All animal experiments conducted in this study were approved by the Institutional Animal Care and Use Committee (IACUC), Chang Gung University and we adhered to their experimental animal care guidelines (protocol number: CGU11-098)

AKT1, TSC1, and TSC2 (Tuberous Sclerosis Complex 1 and 2), which encode the proteins hamartin and tuberin, respectively, are crucial in PTEN-mediated cancer progression [46]

Free Radic Biol Med 96:152165

Our studies also demonstrate that both tripeptides attenuate cell viability in SH-SY5Y cells with GHK demonstrating greater effects ( Figure 6b )

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