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Based on the working hypothesis of P-gp-dependent collateral sensitivity [14,15,16,17], we examined the ability of tamoxifen as a collateral sensitivity drug for two reasons: a) tamoxifen has been previously shown to activate P-gp ATPase at clinically achievable concentration (46 M) [20, 21], and b) tamoxifen is widely used in the treatment of estrogen receptor-positive breast cancer [22]

A.HamptonT

Studies suggest limited cognitive benefits from LR3 alone, though it shows potential for use in combination treatments for Alzheimers, particularly in reducing amyloid- plaques and enhancing microglial activity (8)

Environmental Science & Technology, 59 (33), 1744317456

La tcnica de aplicacin, la frecuencia de uso, la combinacin con otros activos y el nmero de sesiones deben adaptarse a la valoracin profesional de cada caso y a la respuesta esttica observada