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Overexpression of PSR-1 was sufficient to increase axonal fusion rate in young animals treated with ML162 (Fig

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The pathological shift toward M1 polarization results in heightened secretion of pro-inflammatory cytokines and enzymesincluding TNF-, IL-1, IL-6, IL-23, IFN-, inducible nitric oxide synthase and cyclooxygenase-2thereby driving neuroinflammatory processes and contributing to neuronal degeneration 58