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Disclosures: Teiji Kuzuya: Chugai Pharmaceutical Co: Speaking and Teaching, Eisai: Speaking and Teaching, Eli Lilly Japan: Speaking and Teaching, AstraZeneca: Speaking and Teaching, Naoto Kawabe: Nothing to Disclose, Yoshiki Hirooka: Nothing to Disclose 1822 A COMPARATIVE VALIDATION OF CLINICAL PREDICTION SCORES FOR HEPATOCELLULAR CARCINOMA IN STEATOTIC LIVER DISEASE WITHOUT CIRRHOSIS Catherine Mezzacappa 1 Janet Tate 1 Tamar Taddei 1 Amy Justice 1 , 1 Yale University Background: Many clinical risk scores to predict hepatocellular carcinoma (HCC) have been assessed in cohorts without known cirrhosis or viral hepatitis, whose HCC risk is driven by steatotic liver disease (SLD)

Deze zogenoemde NAD+-afhankelijke enzymen zijn betrokken bij belangrijke cellulaire processen zoals DNA-schadeherstel, genexpressie, glucosehomeostase, celoverleving en communicatie tussen cellen