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Anakinra is a recombinant, non-glycosylated human IL-1 receptor antagonist, which has a highly safe profile and large dosages have been utilized even in patients with severe viral illnesses, such as EBV, H1N1, and Ebola [83]

The tablet press should be equipped with pressure regulation and speed control functions to ensure that the hardness and weight differences of the tablets meet the standards

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The limitation of chitosan nanoparticles is that their release rate is strongly affected by particle size and drug loading, and chitosan nano-delivery systems with higher drug loading can fail to pass through the BBB because of the large particle size

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