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Prednisolone suppresses the immune system, but its long-term use at high doses causes a multitude of side effects, including glucose intolerance and diabetes, weight gain, osteoporosis, muscle weakness, hypercholesterolemia, and cataract formation

FRAP measures the degree of residual Fe 2+ generated from the reduction of Fe 3+

NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1 stabilization by inhibiting prolyl hydroxylases activity

Also, n-3 lowers the increased caspase-3 and calpain activity detected by p-nitroanilin absorbance and calcium- and non-calcium-dependent fluorescence in ethanol conditions, reducing cell injury, neurodegeneration, brain hemorrhage, congestion, necrosis, leukocytosis and microglia activation (43)

Persons with increased exposure to toxic substances - Glutathione helps to cleanse the body of toxins and heavy metals, which is especially important for those who live in urban environments or work in industries