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NNMT participates in several differentiation processes including naive-to-primed human embryonic stem cell transition, myogenesis, and both epithelial- and neural-mesenchymal transition in several cancers

While the energetic effects fade after 2 to 4 weeks, vitamin B12 itself continues to be stored in the liver and can remain available for years

Research suggests that it may influence lipid metabolism and fat oxidation processes, primarily through pathways involved in lipolysis and energy utilization without directly stimulating growth hormone or IGF-1 activity

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