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Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

10.1093/hmg/ddz009 104 PinedaJ

doi: 10.1186/ar2514 67 RichardsonSMKalamegamGPushparajPNMattaCMemicAKhademhosseiniAet al

Kim SJ, Park C, Han AL, Youn MJ, Lee JH, Kim Y, et al

The inhibition is competitive glutathione competes with tyrosine (the amino acid tyrosinase acts on) for enzyme binding sites which is why the relationship between dosing, delivery method, and effect is not linear