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By correlating structural data with biochemical activities, we find that Ran-GTP, but not Ran-GDP, constrains the solenoid structure of importin , closing high-affinity FG-binding pockets and displacing import cargos through allosteric crosstalk between the concave and convex surfaces

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Since its the summertime and my legs are exposed when wearing shorts and bathing suits, I was nervous about my scars darkening as I tanned so I continued using the serum (along with applying my SPF) to prevent them from regressing

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