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Cisplatin-mediated inhibition of glycolysis led to increased cellular glucose levels Using LC-MS/MS, the expression level of enzymes involved in glycolysis, phosphofructokinase platelet, phosphoglycerate kinase 1, aldolase A, phosphoglucomutase 1, triosephosphate isomerase 1 pseudogene 1, enolase 1, glyceraldehyde-3-phosphate dehydrogenase, and pyruvate kinase muscle 2, were determined after 6 and 24 h of cisplatin treatment (Fig 4D) and found to be down-regulated compared to the control

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Its generally advised to alternate retinol and copper peptides to avoid reduced efficacy or irritation

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