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GENUS stimulates oligodendrogenesis and reduces OL loss In the CPZ model, oligodendroglia cell death occurs shortly after the administration of CPZ, which translates into a profound demyelination process evident in multiple brain structures including in the CC and neocortex 54

There is controversy in literature concerning which structures primarily dilate through NVC processes, as well as the timing and sequence of dilation

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lignans such as secoisolariciresinol are considered phytoestrogen