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16 Among children ascertained because of clinical symptoms, the two most commonly reported variants are a seven-base deletion/three-base insertion (c.98_104delinsTCC) in exon 2, occurring in at least one allele in approximately 50% of individuals, and p.Arg538Cys in exon 4, occurring at least once in 30% of children

At both 14- and 16-weeks post-inoculation, IL-4 and IL-10 were upregulated in wild-type group, while IL17, IFN, CXCL9, CXCL10, and TNF were also upregulated

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