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We found ABC-transporters and P-type ATPases to be commonly associated with Cd and Hg tolerance, which is supported by previous functional studies among members of these gene families playing large roles in heavy metal transport across membranes and isolation in vacuoles

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When mice were treated with saline after 30 minutes of treatment with 200 mg/kg CEF, in home cages, no significant effect over phase [F (1, 7) = 1, p = 0.3506], between treatments [F (1,7) = 0.0.01810, p = 0.8968], or between phase and treatment [F (1, 7) = 0.7249, p = 0.4227

Thus, glutamine deprivation suppresses cancer growth and even induces cell death in several cancers 6,7