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If the pain is the result of excessive immobility or stiffening, the physician may indicate dopaminergic therapy, physiotherapy, and an exercise program that places strong emphasis on range of motion to prevent the development of musculoskeletal problems in the future

Alternatively, patients may present with peripheral sensory neuropathy as a result of cumulative dose

Immunoblotting Immunoblotting after sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) of the cytosolic fractions to confirm the absence of any mitochondrial protein, was carried out using standard protocols, with antibodies specific for yeast cytosolic glucose-6-phosphate dehydrogenase (anti-G6PD, Sigma-Aldrich, A9521, 1:7500) and mitochondrial heat shock protein 60 (anti-Hsp60, Abcam, ab59458, 1:1000)

Discovery of a bioactive inhibitor with a new scaffold for cystathionine gamma-lyase