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See also this post on how CR appears to protect bone against age-related decline in bone quality /microarchitecture, for which the available human evidence is now in support, or at least to which it offers no contradiction.(35) Menatetrenone seems promising for CR-related low bone mass, as the actual MASS of bone is constrained by low energy intake, whereas menatetrenone primarily appears to reduce risk by preseving QUALITY -- a more likely viable strategy.Arginine and lysine: these have been found to be surprisingly effective in reducing AGE and AGE-induced complications of diabetes, especially in the kidneys but also apparently in the heart (6-12a)

McLeod DSA, Cooper DS

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L-cystathionine, an amino acid mainly produced during the conversion of methionine to cysteine, which can protect against Hcy-induced mitochondria-dependent apoptosis in HUVECs ( 7

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