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Naloxone dosing in non-cardiac arrest opioid overdose The goal with naloxone administration is to avoid worsening respiratory depression, aspiration and cardiac arrest on the one hand, while on the other hand avoiding sending the patient into severe opioid withdrawal and an agitated state

And it is exactly the kind of practical detail that separates researchers who get consistent results from those who wonder why their protocol feels different every week

This treatment leaves behind a trail of people who are forced to face paralyzing pain, chronic fatigue and serious mental damage