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A livello trascrizionale, PPAR attiva geni coinvolti nell'ossidazione degli acidi grassi (tra cui CPT1/2 e deidrogenasi per diverse lunghezze di catena), in particolare in condizioni di maggiore richiesta energetica e in specifiche fasi fisiologiche (es

As the pulmonary vascular resistance drops in the first few days of life, more blood flows to the lungs causing pulmonary congestion, reduced systemic flow causing tissue hypoxemia, metabolic acidosis, shock or even death

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Furthermore, NAC led to a significant decrease in both total cholesterol and low-density lipoprotein levels, whereas metformin only led to a decrease in total cholesterol levels