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The Lancet HIV .PMID 31611038Read source Stanley TL, Falutz J, Mamputu JC, et al

Important Considerations for Combining NAD+ and AOD9604 Despite the theoretical appeal, several crucial points must be considered when exploring the combination of NAD+ and AOD9604: Lack of Direct Combined Research: The most significant caveat is the current lack of extensive human clinical trials specifically investigating the combined effects of NAD+ precursors and AOD9604

This is an unusual mechanism of drug interactions, since usually displacement from albumin will expose more drug to be metabolized (leading to re-equilibration)

Vitamin B12 helps support neurotransmitters, like serotonin and dopamine, which play a role in regulating your mood and alleviating stress

J Biol Chem 272:1911519124