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Each mouse was tested in duplicate through stimulation with RBD protein (10 g/mL), using Concanavalin A (Sigma-Aldrich, No

8 Conclusion Gut dysbiosis plays a pivotal role in the pathogenesis of metabolic dysfunction-associated PCOS, with microbial imbalance closely linked to hyperandrogenemia, insulin resistance, and ovulatory dysfunction

Once initiated, apoptosis involves a cascade of events such as mitochondrial cytochrome c release, activation of caspases, and fragmentation of nuclear DNA (59)

Ladarixin, an inhibitor of the interleukin-8 receptors CXCR1 and CXCR2, in new-onset type 1 diabetes: a multicentre, randomized, double-blind, placebo-controlled trial

152 At low peptide concentrations, these copolymers exhibit -sheet stabilization within internal aqueous compartments, while higher concentrations induce copolymerization with lipid peptides, disrupting the -sheet secondary structure