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Additionally, RNA sequencing revealed increased expression of the circular RNA hsa_circ_0131235 of IGF-2R in the middle temporal cortex with high AD pathology, indicating a significant association with AD pathology [147]

ROS elimination Antioxidant systems necessitate the presence of antioxidants to counterbalance free radicals and neutralize oxidants

Silymarin also reduces ROS production by raising superoxide dismutase (SOD) activity in lymphocytes and erythrocytes

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4,5,6,7-tetrabromo-2-azabenzamidazole (TBB), which specifically inhibits casein kinase 2 (CK2), was selected and discovered to preferentially trigger apoptosis in Zmpste24 / cells