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Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial

The progressive degeneration or dysfunction of RPE cells, which is a hallmark of multiple retinal disorders, invariably causes vision loss or even permanent blindness due to the absence of regenerative capacity (80) ( Table 1 )

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doi: 10.1099/00221287-148-4-1119 39 MavrodiD

With the continuous emergence of novel biologics and small molecules, clinical decision-making must integrate disease conditions, medical history, comorbidities, and safety considerations to develop precise sequential strategies [330, 331]