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Coman, A

Integr Blood Press Control

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However, so far, there is a lack of longitudinal studies illustrating whether poor vascularization and low-level expression of VEGF are the cause of poor healing or merely the sign of poor healing in degenerative tendons ( We cannot deny the importance of early neovascularization for nutrition at the injury site, and therefore, we can identify VEGF-mediated ECM degradation as a negative side-effect accompanied by neovascularization during the remodeling phase ( When a tendon lesion is fully healed, newly formed blood vessels usually regress, and the prolonged presence of blood vessels is thought to result in an adverse healing microenvironment

Plant Cell Environ 35:259270