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Figure 1 Drugs and Treatment Schedule VPA (Cayman Chemical, USA) was dissolved in saline at a concentration of 250 mg/ml and administered at a dose (500 mg/kg) and time (gestational day 12.5) that have been shown to induce autistic-like behavioral changes in the offspring ( 45 , 46 )

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While circular dichroism (CD) analysis confirmed that CD44 I8 WT forms a G4 structure with a typical CD pattern of RNA G4 that is dependent on the buffer conditions, the mutant CD44 I8 Mut did not (Supplementary Fig

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