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Cancer 6 , 2437 (2006)

and (ii) induces a quantitative rise of Nrf2 and glutathione that could only be achieved by the highest non-toxic concentrations of the potent experimental Nrf2-activator DEM

In contrast, high molecular weight soluble A aggregates are more likely to induce microglial activation, resulting in neuroinflammatory responses (Figueiredo et al., 2013)

Coincidentally, it was noticed that the same intrinsic diseases as well as maladaptive changes in form and function also occur spontaneously with advancing age