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A small number of patients proceeded to HSCT (n = 7), which was associated with more favorable DFS and OS, compared with patients who continued on chemotherapy and radiation therapy.[31] Evidence (HSCT): A retrospective, registry-based study compared the outcome of patients treated with either HLA-matched sibling transplants or chemoradiation therapy as in the POG studies above.[224][Level of evidence C2] This study included transplant of both early ( 75%), transplant is generally not recommended by the COG for this group

Moreover, given the substantial interindividual variability in EC metabolism, integrating host and microbial factors into personalized nutrition strategies will be critical for maximizing therapeutic benefits

10.1093/cvr/cvab161 44 ChongS

Although the data suggest an important role of RNS-mediated lipoic modifications in driving this inhibition, several other potential contributing mechanisms are worth considering

A meta-analysis of nutritional supplementation for management of hospitalized alcoholic hepatitis