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It is a commonly used over-the-counter treatment for BPH and its mechanism of action is felt to be similar to that of 5-alpha reductase inhibitors

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All statistical analyses (except for RNA-seq) were performed using GraphPad Prism (version 9), with one-way ANOVA and Tukeys post hoc test for multiple group comparisons and two-sided MannWhitney test for two-group comparisons, assuming a two-tailed distribution

Symptoms of toxicity include tremors, confusion, nausea, and irregular heartbeat