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Because it was not yet known whether sargramostim would be approved for additional indications and dosages, as indicated in the information provided by the applicant, and the available data did not provide enough information for CMS to determine whether Leukine had unique circumstances that would prompt an increase in the applicable percentage, we did not propose an increase in the applicable percentage for the drug in the CY 2025 PFS proposed rule, and stated the applicant may reapply in a future application cycle when more information becomes available

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Sotalol remains a guideline-supported option for patients with ischemic cardiomyopathy who cannot tolerate amiodarone and have shown superior efficacy in suppressing VT in arrhythmogenic right ventricular cardiomyopathy (11)(45)

doi: 10.1038/nature07039