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4th edition, pp

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Further studies are required to elucidate the molecular basis of Cr interactions in various metabolic pathways

For instance, the GPx2 promoter contains so-called antioxidant response elements that confer sensitivity to oxidative stress via the Nrf2/Kelch-like ECH-associated protein 1 (Keap1) system (Banning et al., 2005)

Furthermore, we observed no significant effect on mtDNA copy number in the knockout or treatment, consistent with unchanged MIC60 expression levels, which is known to play a role in nucleoid organization (Fig