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Pirenoxine Pirenoxine is a xanthomatin that possesses strong antioxidant properties and can slow down lens opacity as revealed in several in vitro and in vivo studies [65,66,67,68]

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In clinical populations, reduced BDNF levels in the entorhinal cortex and hippocampus have been correlated with low Mini-Mental State Examination (MMSE) scores, thereby underscoring the relationship between neurotrophic support and cognitive decline in AD (Wu et al., 2016)

ACKNOWLEDGEMENTS We would like to thank the Caenorhabditis Genetics Center (funded by the National Institutes of Health Office of Research Infrastructure Programs: P40OD010440), as well as the National Bioresource Project (NBRP) for C

(2013), GbE, and some of its constituents, such as ginkgolide B and bilobalide, protected neurons against apoptotic and excitotoxic damage