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These results are promising, but clinical trials are needed to see if curcumin has the potential to treat PV

Hum Mutat 25:196206 Joyner AL, Herrup K, Auerbach BA, Davis CA, Rossant J (1991) Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the en-2 homeobox

Working from the bottom-up, the staging approach may benefit from therapeutic models that are developmental in nature, in order to achieve the kind of personalized-medicine it seeks to promote (McGorry, 2013)

Flavonoids inhibit platelet function through binding to the thromboxane A2 receptor