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Although glucuronide conjugates have lower biological activity, excessive accumulation may cause unpredictable effects or compete with endogenous substrate metabolism (257)

Because it is a single compound rather than a blend, there is no multi-component composition table to break down but the mechanism is worth mapping out, because it explains why the research doses are so small and why the effect is gradual rather than acute

Stochasticity accelerates nematode egg development

Jamei M, Dickinson GL, Rostami-Hodjegan A (2009) A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: a tale of `Bottom-Up vs`Top-Down recognition of covariates

PMID: 30724573