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Microorganisms 9(2):353 De Vadder F, Kovatcheva-Datchary P, Goncalves D, Vinera J, Zitoun C, Duchampt A et al (2014) Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits

However, it has been believed for many years that there was negligible interaction between the immune system and the brain parenchyma since the BBB limited the escape of antigens from and the entry of lymphocytes into the central nervous system

doi: 10.2147/IJN.S114205

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