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Nat Rev Cardiol 2022;19:723736

Eur J Cardiothorac Surg 25: 839843

The lysosomal cysteine proteases in MHC class II antigen presentation

The resulting inactivation efficiency ( k inact to K i ) was 2.43 10 3 min 1 M 1 for CYP2B6 and 1.64 10 2 min 1 M 1 for CYP2D6, respectively, indicating greater inactivation efficiency toward CYP2D6