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Since then, several clinical studies have shown its safe and effective use - but the pharmacuetical companies have decided not to (yet) pursue FDA-Approval (likely because each new FDA-Approval costs several million dollars to go through the process, and because there are a good deal of drugs used off-label in the way tranexamic acid is for melasma, especially when the drug has a long history of safety and efficacy, as is in this case)

GHK-Cu is water-soluble

In some cases, a Vitamin B12 deficiency may also be a factor

The Vegan Society and NHS recommend that vegans take a B12 supplement or consume fortified foods regularly

Most people experience relief for several months, with some not requiring additional treatment for as long as a year