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( a ) The expression of cytosolic or nuclear IDO1 in MCF-7 cells treated with 50 or 100 M H 2 O 2 , or combined with 5 mM NAC was analyzed by Western blot

A key extrinsic pathway component is the death receptor Fas (CD95), which, upon binding to Fas ligand (FasL/CD95L), recruits the adaptor protein FADD (Fas-associated death domain protein) and procaspase-8 to form the death-inducing signaling complex (DISC)

African markets specifically show emerging interest as rising incomes and expanding retail infrastructure in Nigeria, Kenya, and South Africa create accessibility for international brands, though price-sensitive local competitors remain dominant

doi: 10.1016/j.biopha.2024.116783 183 GreenwoodHEWitneyTH

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