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Both Uricase and RBC@SeMSN@Uri distributions were examined by injecting Cy7-labeled uricase and collecting major organs 4 h after administration for imaging

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Studies in ischemia-reperfusion injury mouse models show that ACSL4 expression is upregulated in ischemic tissues, and inhibiting ACSL4 suppresses ferroptosis by reducing lipid peroxidation, significantly mitigating tissue and organ damage [32]

& Nagano, T

For example, in a study by Liu et al., a novel dual receptor recognizing the cell-penetrating peptide R8-dGR, which could bind to both integrin v 3 and neuropilin-I receptors, was used to functionalize liposomes [154]