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Eighty patients with MDD, 82 patients with BD (total 162 patients) and 96 healthy controls were enrolled in this study and genotyped using a Real Time-Quantitative Polymer Chain Reaction (RT-qPCR)-based method

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Theyre essential for obtaining energy, regulating hormones, forming red blood cells, breaking down blood sugar, metabolizing food, growing skin, hair, and nails, and promoting cell growth

In vivo, this cascade-regulated metabolic inhibition produced potent tumor suppression with minimal systemic toxicity, underscoring the advantage of integrating photothermal control with multi-level metabolic targeting

These results suggest that STN-DBS acts on the PD circuit by specifically downregulating SCAN hyperconnectivity