glutathione and parkinsons disease metabolism Parkinson's glutathione metabolism and parkinson's disease

As a serotonin-noradrenaline-dopamine reuptake inhibitor, tesofensine works at the level of the brain by suppressing appetite and increasing resting energy expenditure (your basal metabolic rate)

VIP (Vasoactive Intestinal Peptide) : Neurologic peptide that can reduce systemic inflammation and promote brain healing

Tumour Biol 37:14271436 Repnik U, Turk B (2010) Lysosomal-mitochondrial cross-talk during cell death

The therapeutic-loaded coacervates bypass classical endocytic pathways to enter the cytosol, where they undergo glutathione-mediated release of payload, the bioactivity of which is retained in the cell, while mRNAs exhibit a high transfection efficiency

This effect is a consequence of the increase in 2,3-bisphosphoglycerate concentration in red blood cells