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The pathogenic mechanisms underlying AD encompass microglia-induced inflammation, elevated intracellular calcium levels, disruption of antioxidant defense systems, cholinergic dysfunction, overactivation of glutamate receptors, and amplification of the inflammatory response (88)

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Invest Ophthalmol Vis Sci 54(12):73957401 Das S et al (2018) Identification of a novel gene in ROD9 island of Salmonella enteritidis involved in the alteration of virulence-associated genes expression

COX exists in two isoforms: COX-1, which is constitutively expressed, and COX-2, an inducible enzyme encoded by prostaglandin-endoperoxide synthase 2 (PTGS2)