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( n = 120) showed LV dilatation (16%) and ventricular arrhythmias (25%), even in the absence of significant volume overload, suggesting another pathophysiological mechanism ( Besides focal fibrosis, limited data are available regarding the presence of diffuse interstitial fibrosis in patients with MVP, which can be associated with diastolic and systolic impairment

the amount of TMA in the reaction mixture may be between 1 and 3 equivalents, preferably between 1 and 2.5 equivalents

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