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A.Gomez-GiroG.KrgerR.BologninS.et al

However, some polysaccharides exhibit high solubility and poor film-forming ability, leading to premature drug release and reduced colonic targeting

Gorski JA, Talley T, Qiu M, Puelles L, Rubenstein JL, Jones KR

Microbiology 153: 32113217

No microagulhamento, por exemplo, o aumento da permeabilidade cutnea favorece a absoro do ativo, potencializando respostas como melhora da textura, aumento da densidade drmica e recuperao mais rpida do tecido