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That approach improves interpretability, reduces unnecessary escalation, and keeps the work anchored in a research-only context where safety controls and documentation are part of the protocol, not an afterthought

Tesamorelin Overview Primary Use: Initially developed to reduce excess abdominal fat in HIV patients

The essentiality of this pathway in PDAC and the fact that it is dispensable in normal cells may provide novel therapeutic approaches to treat these refractory tumours