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Utilizing two discrete murine HCC models, we found that myeloid-specific deletion of Samhd1 promotes HCC progression through increased PD-L1 expression and CXCL1/2-mediated recruitment and activation of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs)

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In terms of cross-sectional remission, we observed the rates of 42.31% ( n = 11 of 26) a 1-month, 50% ( n = 13 of 26) at 3-months, and 60% ( n = 15 of 25) at 6 months

Silymarin is the active compound group extracted from the seeds and fruit of Silybum marianum

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