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The active metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), must form a VDR-RXR heterodimer with RXR after binding to vitamin D receptor (VDR), so as to effectively recognize and bind to VDREs in the promoter region of the target gene and initiate transcriptional regulation

Chen P, Wu B, Ji L, Zhan Y, Li F, Cheng L, et al

UVA1 radiation triggers two different final apoptotic pathways

When it comes to the inflammatory stage, the Treg cells exert an anti-inflammatory effect through the inhibition action of CD8 + Th and CD4 + T cells

Inflammation-associated nitrate facilitates ectopic colonization of oral bacterium Veillonella parvula in the intestine [J]