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This, together with the discovery of high-affinity binding sites for [ 125 I]Ang IV in the central nervous, vascular and renal systems, 16, 116, 117 has led to the concept of a novel Ang receptor subtype: the AT 4 receptor, 14 which was convincingly shown to be insulin-regulated aminopeptidase (IRAP), a membrane-anchored zinc-dependent metallopeptidase

10.1097/01.alc.0000169265.36440.ee 25

Differential expression of rice Lambda class GST gene family members during plant growth, development, and in response to stress conditions

Cassard AM, Ciocan D

This was fully investigated in 1849, by British physician Thomas Addison, from which it acquired the common name of Addison's anemia