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Hence, the study proposed that targeting miR-204-5p could have therapeutic potential for managing HCC [130]

Possible mechanisms by which EBNA1 could induce ROS, include increasing levels of oxidases (e.g., NOX1 and NOX2) or affecting the levels of antioxidant enzymes, such as SOD1, peroxiredoxin 1, peroxiredoxin 6, or glutathione S-transferase

Treatment of liver disease with TCM and natural products: targeting the gut-liver axis The human GM consists mainly of six major phyla: Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, Verrucomicrobia, and Fusobacteria [110]