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Recent studies have demonstrated that higher urinary levels of these chemicals correlate with impaired semen parameters and increased oxidative stress, suggesting a detrimental effect on male fertility (79, 80)

Since many adult diseases have fetal origin, application of IHT in pregnancy or to the infants might prevent development of various diseases in later life ( Accumulated evidence from ongoing preclinical research clearly demonstrates that IHT has a powerful cerebro- and neuroprotective application

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The top four abundant elements involved in the hormone and stress responses are - MBS element with 85 instances, 83 instances of the defense and stress-responsive element (TC-rich repeats), 64 instances of HSE element and 63 instances of TCA element (Table S5)