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MiR-9, miR-153 and miR-124 are down-regulated by acute exposure to cocaine in a dopaminergic cell model and may contribute to cocaine dependence

4).8 Adolescent patients In the ALLEGRO-2b/3 trial, 15% of the population consisted of hard-to-treat adolescents with SALT 50% (severe AA), a mean disease duration of 6.5 years, and 40% with AT or AU.8 Although limited by small sample size, the results were consistent with those in the overall study population

doi: 10.1111/epi.17969 36 VegrimHMDreierJWAlvestadSGilhusNEGisslerMIglandJet al

While this is just one case, it shows how combining treatments can sometimes succeed when standard methods fail