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Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

Maggiorini, M., Buhler, B., Walter, M

Tumor-draining lymph nodes are survival niches that support T cell priming against lymphatic transported tumor antigen and effects of immune checkpoint blockade in TNBC

Interestingly, while lysosomes in ACT-treated WT cells also display lysosomal acidification impairment, the lysosomal pH in ATP6AP1 KO cells remained unaffected by ACT treatment